[Veterinary drug name] Common name: Sulfuric acid colistin soluble powder

Product Name:

English name: Colistin Sulfate Solve Powder Chinese pinyin: Liusuan Nianjunsu Kerongxingfen

[Main ingredient] Colistin

[Appearance] This product is a white or off white powder.

[Pharmacological Effects] Pharmacodynamic colistin belongs to the peptide antibacterial class and is an alkaline cationic surfactant that interacts with bacterial cells

The interaction between phospholipids inside the membrane infiltrates into the bacterial cell membrane, disrupting its structure and causing changes in membrane permeability, leading to bacterial death and producing bactericidal effects. This product has strong antibacterial effects on Gram negative bacteria such as aerobic bacteria, Escherichia coli, Haemophilus, Klebsiella, Pasteurella, Pseudomonas aeruginosa, Salmonella, Shigella, etc. Gram positive bacteria are usually insensitive. There is complete cross resistance with polymyxin B, but no cross resistance with other antibiotics.

Pharmacokinetics: Oral administration is almost not absorbed, but non gastrointestinal administration is rapidly absorbed. The drugs that enter the body can quickly distribute into the heart, lungs, liver, kidneys, and skeletal muscles, but are not easily able to enter the brain, spinal cord, chest cavity, joint cavity, and infected lesions. Mainly excreted through the kidneys.

Drug Interaction 1 (1): Co administration with neuromuscular blocking agents such as muscle relaxants and aminoglycosides may cause muscle weakness and respiratory arrest.

(2) It has a synergistic effect with integration agents (EDTA) and cationic cleaners on Pseudomonas aeruginosa, and is often used in combination for local applications

The treatment of partial infection.

[Function and Use] Peptide antibiotics. Mainly used to treat intestinal infections caused by Gram negative bacteria. [Usage and Dosage] Calculate based on this product. Mixed drink: 0.4-0.6g for pigs and 0.2-0.6g for chickens per 1L of water;

Mixed feeding: 0.4-0.8g per 1kg of feed for pigs

[Adverse reactions] No adverse reactions have been observed when using according to the prescribed dosage.

[Precautions] (1) Chickens that lay eggs for human consumption should not be used during the delivery period. (2) Continuous use should not exceed one week. [Rest period] Pigs and chickens for 7 days.

[Specification 1100g: 10g (300 million units)]

Packaging 500g/bag

Store in a dark, sealed, and dry place. [Production Date 1 [Production Batch Number] [Expiration Date]