[Common name of veterinary medicine: Enrofloxacin soluble powder]

Product Name:

English name: Enrofloxacin Solve Powder Chinese pinyin: Ennuoshaxing Kerongxingfen

[Main ingredient] Enrofloxacin

[Appearance] This product is a white or light yellow powder.

Pharmacodynamic effects: Enrofloxacin is a broad-spectrum bactericidal drug specifically designed for fluoroquinolone animals. For Escherichia coli, Salmonella

Klebsiella, Pasteurella, Proteus, Serratia marcescens, Corynebacterium pyogenes, Staphylococcus aureus, Mycoplasma, Chlamydia, etc. all have good effects, but have weak effects on Pseudomonas aeruginosa and Streptococcus, and weak effects on anaerobic bacteria. Has a significant antibacterial effect on sensitive bacteria. The antibacterial mechanism of this product is to inhibit bacterial DNA gyrase, interfere with bacterial DNA replication, transcription, and repair recombination, and prevent bacteria from growing and reproducing normally and dying.

Most animals can absorb this product well when taken orally in pharmacokinetics. The bioavailability of chicken oral administration is 62.2% -84%, widely distributed in the body, and can enter tissues and body fluids (including bones) well. Except for cerebrospinal fluid, the drug concentration in almost all tissues is higher than that in plasma. Liver metabolism is mainly the production of ciprofloxacin by removing the ethyl group of 7-piperazine ring, followed by oxidation and glucuronic acid binding. It is mainly excreted through the kidneys (through tubular secretion and glomerular filtration), with 15% -50% excreted in its original form in the urine. The half-life of this product for chicken oral administration is 9.1-14.2 hours.

[Drug Interaction] (1) It has a synergistic effect when used in combination with aminoglycosides and broad-spectrum penicillin.

(2) Ca, Mg, Fe, Ab and other heavy metal ions can chelate with this product, affecting absorption.

(3) Combined use with tea city and caffeine can inhibit the metabolism of the latter, resulting in an abnormal increase in the concentration of theophylline and caffeine in the blood,

Even exhibiting symptoms of theophylline poisoning.

(4) It has an inhibitory effect on liver enzymes, and when combined with drugs metabolized in the liver, it can reduce their clearance rate and blood drug concentration

rise.

(5) Probenecid can inhibit its renal tubular secretion and excretion, prolonging its half-life.

[Function and Use] Quinolone antibiotics. Used for bacterial diseases and mycoplasma infections in chickens and racing pigeons.

[Usage and Dosage] Calculate based on this product. Mixed drink: 0.5-1.5g of chicken per 1L of water, twice a day, for 3-5 consecutive days; Racing pigeon 5G, continuous use

3-5 days.

Adverse reactions (1) can cause degeneration of cartilage in young animals, leading to claudication and pain.

(2) Digestive system reactions include vomiting, abdominal pain, and bloating.

(3) Skin reactions include erythema, itching, urticaria, and photosensitivity.

[Note 1 (1) Chickens that lay eggs for human consumption should not be used during the egg laying period.].

(2) Black bone chicken is prohibited.

The rest period for chickens is 8 days. [Specification: 15%]

Packaging 500g/bag

Store in a dark, sealed, and dry place.

[Production date [Production batch number] [Expiration date]